Thalidomide-propargyl-MeOH is an E3 ligase ligand-linker conjugate featuring a cereblon (CRBN) ligand and a propargyl linker. This compound is designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs), facilitating targeted protein degradation. Its application in biochemical research enables the investigation of protein dynamics and potential therapeutic interventions in various diseases.
Thalidomide-propargyl-MeOH is an E3 ligase ligand-linker conjugate featuring a cereblon (CRBN) ligand and a propargyl linker. This compound is designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs), facilitating targeted protein degradation. Its application in biochemical research enables the investigation of protein dynamics and potential therapeutic interventions in various diseases.
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