Thalidomide-Propargyne-PEG2-COOH is an E3 ligase ligand-linker conjugate that combines a Thalidomide-derived cereblon ligand with a PEG-based linker suitable for PROTAC applications. This compound features an alkyne moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc). It serves as a valuable tool for research in targeted protein degradation and the development of innovative therapeutic strategies.
Thalidomide-Propargyne-PEG2-COOH is an E3 ligase ligand-linker conjugate that combines a Thalidomide-derived cereblon ligand with a PEG-based linker suitable for PROTAC applications. This compound features an alkyne moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc). It serves as a valuable tool for research in targeted protein degradation and the development of innovative therapeutic strategies.
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