Thalidomide-S-COOH is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN)-based ligand and a linker moiety. This compound facilitates the synthesis of Proteolysis Targeting Chimeras (PROTACs), which are innovative tools for targeted protein degradation. Its applications include fundamental research in cellular signaling pathways, drug development, and therapeutic interventions in various diseases.
Thalidomide-S-COOH is an E3 ligase ligand-linker conjugate that incorporates a cereblon (CRBN)-based ligand and a linker moiety. This compound facilitates the synthesis of Proteolysis Targeting Chimeras (PROTACs), which are innovative tools for targeted protein degradation. Its applications include fundamental research in cellular signaling pathways, drug development, and therapeutic interventions in various diseases.
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