Thanatin is an inducible cationic antimicrobial peptide that targets microbial membranes. It exhibits broad-spectrum antimicrobial activity against both Gram-negative and Gram-positive bacteria, as well as various fungi, with minimum inhibitory concentrations (MICs) ranging from 0.3 to 40 µM. Thanatin functions by competitively displacing divalent cations from the bacterial outer membrane, resulting in membrane disruption and enhanced permeability. This peptide is valuable for research applications in antimicrobial resistance, infection mechanisms, and the development of novel antibacterial agents.
Thanatin is an inducible cationic antimicrobial peptide that targets microbial membranes. It exhibits broad-spectrum antimicrobial activity against both Gram-negative and Gram-positive bacteria, as well as various fungi, with minimum inhibitory concentrations (MICs) ranging from 0.3 to 40 µM. Thanatin functions by competitively displacing divalent cations from the bacterial outer membrane, resulting in membrane disruption and enhanced permeability. This peptide is valuable for research applications in antimicrobial resistance, infection mechanisms, and the development of novel antibacterial agents.
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