Theleganbanin B is a p-terphenyl derivative isolated from Thelephora ganbajun, demonstrating potent inhibition of pro-inflammatory cytokines TNF-α, IL-6, and IL-1β in LPS-induced BV-2 microglial cells. This compound also inhibits the phosphorylation of JAK2/STAT3, highlighting its regulatory role in inflammatory signaling pathways. Theleganbanin B presents potential for research in the context of neurodegenerative diseases, offering insights into therapeutic strategies against neuroinflammation.
Theleganbanin B is a p-terphenyl derivative isolated from Thelephora ganbajun, demonstrating potent inhibition of pro-inflammatory cytokines TNF-α, IL-6, and IL-1β in LPS-induced BV-2 microglial cells. This compound also inhibits the phosphorylation of JAK2/STAT3, highlighting its regulatory role in inflammatory signaling pathways. Theleganbanin B presents potential for research in the context of neurodegenerative diseases, offering insights into therapeutic strategies against neuroinflammation.
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