Thioflavin T is a cationic benzothiazole dye that selectively binds to β-amyloid fibrils, resulting in a significant increase in fluorescence. The dye exhibits an excitation maximum at approximately 385 nm when unbound and around 450 nm when bound to amyloid, with emission maxima of approximately 445 nm and 485 nm, respectively. It is widely used in research to detect and study amyloid deposition in tissues, contributing to the understanding of neurodegenerative diseases such as Alzheimer's.
Thioflavin T is a cationic benzothiazole dye that selectively binds to β-amyloid fibrils, resulting in a significant increase in fluorescence. The dye exhibits an excitation maximum at approximately 385 nm when unbound and around 450 nm when bound to amyloid, with emission maxima of approximately 445 nm and 485 nm, respectively. It is widely used in research to detect and study amyloid deposition in tissues, contributing to the understanding of neurodegenerative diseases such as Alzheimer's.
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