THPP-2

Catalog No.: A42101
PDE10A Inhibitor
THPP-2 is a selective phosphodiesterase 10A (PDE10A) inhibitor, exhibiting a Ki value of 94 nM. This compound is primarily utilized in the investigation of schizophrenia and offers insights into the mechanisms of this mental disorder. By modulating PDE10A activity, THPP-2 aids in the exploration of potential therapeutic strategies for schizophrenia-related pathophysiology.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTHPP-2 is a selective phosphodiesterase 10A (PDE10A) inhibitor, exhibiting a Ki value of 94 nM. This compound is primarily utilized in the investigation of schizophrenia and offers insights into the mechanisms of this mental disorder. By modulating PDE10A activity, THPP-2 aids in the exploration of potential therapeutic strategies for schizophrenia-related pathophysiology.
Product Information
Catalog NumA42101
FormulaC27H27N7O
Molecular Weight465.56
CAS Number1393750-01-0
SMILESO=C(NC=1C=CC=CC1)N2CC=3C(=NC(=NC3CC2)C=4C=CN=CC4)N(C)CCC5=NC=CC=C5
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