THZ1

Catalog No.: A14192

CDK7 Inhibitor

THZ1

THZ1 Chemical Structure

CAS NO. 1604810-83-4

THZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50(binding affinity) of 3.2 nM; inhibits Jurkat cell's proliferation with IC50 of 50 nM

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $56.00

10 mg

Regular Price: $120.00

Special Price $96.00

25 mg

Regular Price: $220.00

Special Price $176.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

THZ1 is a novel selective and potent covalent CDK7 inhibitor with IC50(binding affinity) of 3.2 nM; inhibits Jurkat cell's proliferation with IC50 of 50 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.67 mL 88.33 mL 176.66 mL
0.5 mM 3.53 mL 17.67 mL 35.33 mL
1 mM 1.77 mL 8.83 mL 17.67 mL
5 mM 0.35 mL 1.77 mL 3.53 mL

*The above data is based on the productmolecular weight 566.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14192
Actions Inhibitor
M. Wt 566.05
Formula C31H28ClN7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1604810-83-4
Synonyms THZ-1,THZ 1
SMILES CN(C)C/C=C/C(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl

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