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Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.
| In vitro (25°C) | DMSO | 99 mg/mL (189.45 mM) | |
| Water | Insoluble | ||
| Ethanol | 52 mg/mL (99.51 mM) | ||
| In vivo | 2% DMSO+30% PEG 300+5% Tween 80+ddH2O | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.14 mL | 95.68 mL | 191.35 mL |
| 0.5 mM | 3.83 mL | 19.14 mL | 38.27 mL |
| 1 mM | 1.91 mL | 9.57 mL | 19.14 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.83 mL |
*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11238 |
|---|---|
| Actions | Antagonist |
| CAS No. | 274693-27-5 |
| Formula | C23H28F2N6O4S |
| M. Wt | 522.6 |
| Purity | >98% |
| Synonyms | AZD 6140 |
| SMILES | CCCSC1=NC2=C(C(=N1)N[[email protected]@H]3C[[email protected]]3C4=CC(=C(C=C4)F)F)N=NN2[[email protected]@H]5C[[email protected]@H]([[email protected]]([[email protected]]5O)O)OCCO |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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