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Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.
| In vitro | DMSO | 105 mg/mL (200.93 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 53 mg/mL (101.42 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.14 mL | 95.68 mL | 191.35 mL |
| 0.5 mM | 3.83 mL | 19.14 mL | 38.27 mL |
| 1 mM | 1.91 mL | 9.57 mL | 19.14 mL |
| 5 mM | 0.38 mL | 1.91 mL | 3.83 mL |
*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A11238 |
|---|---|
| Actions | Antagonist |
| M. Wt | 522.6 |
| Formula | C23H28F2N6O4S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 274693-27-5 |
| Synonyms | AZD 6140 |
| SMILES | CCCSC1=NC2=C(C(=N1)N[[email protected]@H]3C[[email protected]]3C4=CC(=C(C=C4)F)F)N=NN2[[email protected]@H]5C[[email protected]@H]([[email protected]]([[email protected]]5O)O)OCCO |
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