Ticagrelor (AZD6140)

Catalog No.: A11238

P2Y12 antagonist

Ticagrelor (AZD6140)

Ticagrelor (AZD6140) Chemical Structure

CAS NO. 274693-27-5

Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.

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50 mg
$80.00
25 mg
$50.00
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Biological Activity

Ticagrelor (AZD6140) is the first reversibly binding oral P2Y(12) receptor antagonist that blocks ADP-induced platelet aggregation.
In vitro (25°C) DMSO 99 mg/mL (189.45 mM)
Water Insoluble
Ethanol 52 mg/mL (99.51 mM)
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.14 mL 95.68 mL 191.35 mL
0.5 mM 3.83 mL 19.14 mL 38.27 mL
1 mM 1.91 mL 9.57 mL 19.14 mL
5 mM 0.38 mL 1.91 mL 3.83 mL

*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11238
Actions Antagonist
CAS No. 274693-27-5
Formula C23H28F2N6O4S
M. Wt 522.6
Purity >98%
Synonyms AZD 6140
SMILES CCCSC1=NC2=C(C(=N1)N[[email protected]@H]3C[[email protected]]3C4=CC(=C(C=C4)F)F)N=NN2[[email protected]@H]5C[[email protected]@H]([[email protected]]([[email protected]]5O)O)OCCO
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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