Catalog No.: A18770

LTC4S inhibitor


TK05 Chemical Structure

CAS NO. 1245734-61-5

TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM.

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Biological Activity

TK05 is a potent and selective inhibitor of leukotriene C4 synthase (LTC4S) with an IC50 of 95 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.48 mL 92.42 mL 184.85 mL
0.5 mM 3.7 mL 18.48 mL 36.97 mL
1 mM 1.85 mL 9.24 mL 18.48 mL
5 mM 0.37 mL 1.85 mL 3.7 mL

*The above data is based on the productmolecular weight 540.99. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18770
Actions Inhibitor
CAS No. 1245734-61-5
Formula C31H25ClN2O5
M. Wt 540.99
Purity >98%
Synonyms TK 05, TK-05
SMILES ClC1=CC=C(N(CC2CC2)C3=CC=C(C(C4=CC(C(O)=O)=C(C(C5=CC=C(OC)C=C5)=O)C=C4)=O)N=C3)C=C1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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