TKIM is a selective inhibitor of the TREK-1 channel, exhibiting an IC50 of 2.96 μM. By binding to the pocket of the intermediate (IM) state of TREK-1, TKIM modulates ion channel activity. This compound is valuable for investigations into the physiological roles of TREK-1 in neurobiology and cardiovascular research, as well as potential therapeutic applications in pain and mood disorders.
TKIM is a selective inhibitor of the TREK-1 channel, exhibiting an IC50 of 2.96 μM. By binding to the pocket of the intermediate (IM) state of TREK-1, TKIM modulates ion channel activity. This compound is valuable for investigations into the physiological roles of TREK-1 in neurobiology and cardiovascular research, as well as potential therapeutic applications in pain and mood disorders.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
