TMX-4100

Catalog No.: A41779
PDE6D Degrader
TMX-4100 is a selective degrader of phosphodiesterase 6D (PDE6D), exhibiting high degradation efficacy with DC50 values below 200 nM in MOLT4, Jurkat, and MM.1S cell lines. This compound demonstrates potential for targeting PDE6D in research related to multiple myeloma, providing a valuable tool for investigating therapeutic strategies in this area.
Grouped product items
Size Price Stock Qty
1mg
$80.00
In stock
5mg
$205.00
In stock
10mg
$335.00
In stock
25mg
$610.00
In stock
50mg
$810.00
In stock
100mg
$1,110.00
In stock
200mg
$1,460.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTMX-4100 is a selective degrader of phosphodiesterase 6D (PDE6D), exhibiting high degradation efficacy with DC50 values below 200 nM in MOLT4, Jurkat, and MM.1S cell lines. This compound demonstrates potential for targeting PDE6D in research related to multiple myeloma, providing a valuable tool for investigating therapeutic strategies in this area.
Product Information
Catalog NumA41779
FormulaC11H10N4O2S
Molecular Weight262.29
CAS Number2367619-63-2
SMILESO=C(C(N1N=NC(C2=CSC=C2)=C1)CC3)NC3=O
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