Toceranib phosphate

Catalog No.: A15263

Toceranib phosphate

Toceranib phosphate Chemical Structure

CAS NO. 874819-74-6

Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.

Availability: In stock

Package Price Qty
10 mg
$45.00
50 mg
$90.00
200 mg
$250.00
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Biological Activity

Toceranib phosphate is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.
In vitro DMSO 2 mg/mL (4.04 mM)
Water 2 mg/mL (4.04 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.22 mL 101.12 mL 202.24 mL
0.5 mM 4.04 mL 20.22 mL 40.45 mL
1 mM 2.02 mL 10.11 mL 20.22 mL
5 mM 0.4 mL 2.02 mL 4.04 mL

*The above data is based on the productmolecular weight 494.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15263
CAS No. 874819-74-6
Formula C22H28FN4O6P
M. Wt 494.45
Solubility DMSO
Purity >98%
Synonyms SU 11654, PHA 291639, SU11654, SU-11654, PHA-291639, PHA291639
SMILES CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)C=C3C4=C(C=CC(=C4)F)NC3=O.OP(=O)(O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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