Toceranib (PHA 291639, SU 11654)

Catalog No.: A11581

c-Kit, PDGFR, VEGFR inhibitor

Toceranib (PHA 291639, SU 11654)

Toceranib (PHA 291639, SU 11654) Chemical Structure

CAS NO. 356068-94-5

Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$90.00
25 mg
$160.00
50 mg
$250.00
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  • Masaya Igase, .et al. Oncolytic reovirus synergizes with chemotherapeutic agents to promote cell death in canine mammary gland tumor, Can J Vet Res, 2016, Jan; 80(1): 21-31 PMID: 26733729

Biological Activity

Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth factor receptor 2, and PDGFRβ.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.23 mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11581
Actions Inhibitor
M. Wt 396.46
Formula C22H25FN4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 356068-94-5
Synonyms PHA 291639, SU 11654, PHA-291639, SU-11654, PHA291639, SU11654
SMILES CC1=C(NC(=C1C(=O)NCCN2CCCC2)C)/C=C\3/C4=C(C=CC(=C4)F)NC3=O

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