Tofimilast is a selective inhibitor of Phosphodiesterase 4 (PDE4) with an IC50 of 0.14 μM. By blocking PDE4 activity, Tofimilast elevates intracellular cyclic adenosine monophosphate (cAMP) levels, contributing to its anti-inflammatory properties. This reagent is valuable for research applications aimed at exploring inflammatory pathways and potential therapeutic interventions in respiratory and autoimmune conditions.
Tofimilast is a selective inhibitor of Phosphodiesterase 4 (PDE4) with an IC50 of 0.14 μM. By blocking PDE4 activity, Tofimilast elevates intracellular cyclic adenosine monophosphate (cAMP) levels, contributing to its anti-inflammatory properties. This reagent is valuable for research applications aimed at exploring inflammatory pathways and potential therapeutic interventions in respiratory and autoimmune conditions.
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