Toll-Like Receptor 7 Ligand II

Catalog No.: A12683

TLR7 Ligand

Toll-Like Receptor 7 Ligand II Chemical Structure

CAS NO. 226907-52-4

Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
50 mg
$2,000.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro .
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.71 mL 158.56 mL 317.13 mL
0.5 mM 6.34 mL 31.71 mL 63.43 mL
1 mM 3.17 mL 15.86 mL 31.71 mL
5 mM 0.63 mL 3.17 mL 6.34 mL

*The above data is based on the productmolecular weight 315.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12683
Actions N/A
M. Wt 315.33
Formula C15H17N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 226907-52-4
Synonyms CL087; SM360320
SMILES COCCOC1=NC2=C(C(=N1)N)NC(=O)N2CC3=CC=CC=C3

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