Tolnaftate

Catalog No.: A11657

Tolnaftate

Tolnaftate Chemical Structure

CAS NO. 2398-96-1

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.

Availability: In stock

Package Price Qty
1000 mg
$50.00
10mM * 1mL in DMSO
$59.00
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Biological Activity

Tolnaftate is a synthetic thiocarbamate used as an anti-fungal agent. It is believed to inhibit the squalene epoxidase, an important enzyme in the biosynthetic pathway of ergosterol (a key component of the fungal membrane) in a similar way to allylamines.
In vitro DMSO 62 mg/mL (201.68 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.53 mL 162.65 mL 325.3 mL
0.5 mM 6.51 mL 32.53 mL 65.06 mL
1 mM 3.25 mL 16.26 mL 32.53 mL
5 mM 0.65 mL 3.25 mL 6.51 mL

*The above data is based on the productmolecular weight 307.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11657
M. Wt 307.41
Formula C19H17NOS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2398-96-1
SMILES CC1=CC(=CC=C1)N(C)C(=S)OC2=CC3=CC=CC=C3C=C2

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