Topoisomerase I/II inhibitor 2 is a potent inhibitor targeting both DNA topoisomerase I and II, demonstrating an IC50 of 9.82 μM in Huh7 cells and 6.83 μM in LM9 cells. This compound effectively reduces xenograft tumor growth in murine models, highlighting its potential utility in liver cancer research. Its dual inhibition mechanism provides a valuable tool for investigating therapeutic strategies in oncology.
Topoisomerase I/II inhibitor 2 is a potent inhibitor targeting both DNA topoisomerase I and II, demonstrating an IC50 of 9.82 μM in Huh7 cells and 6.83 μM in LM9 cells. This compound effectively reduces xenograft tumor growth in murine models, highlighting its potential utility in liver cancer research. Its dual inhibition mechanism provides a valuable tool for investigating therapeutic strategies in oncology.
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