Topoisomerase I Inhibitor 4 is a selective inhibitor of topoisomerase I, effectively targeting the enzyme to disrupt DNA replication. It demonstrates significant anti-proliferative effects on various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. This compound is valuable for cancer research, particularly in studying mechanisms of tumor growth inhibition.
Topoisomerase I Inhibitor 4 is a selective inhibitor of topoisomerase I, effectively targeting the enzyme to disrupt DNA replication. It demonstrates significant anti-proliferative effects on various cancer cell lines, including HepG2, A549, MCF-7, and HeLa, with IC50 values of 1.20 μM, 2.09 μM, 1.56 μM, and 1.92 μM, respectively. This compound is valuable for cancer research, particularly in studying mechanisms of tumor growth inhibition.
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