Topoisomerase I inhibitor 9 is a selective inhibitor of leishmanial topoisomerase IB, demonstrating significant antileishmanial activity against Leishmania donovani promastigotes. The compound exhibits an IC50 value of 34.81 μM, indicating its potential utility in research aimed at developing therapeutic strategies for leishmaniasis. This reagent is valuable for studies focusing on the role of topoisomerases in parasite biology and drug discovery efforts targeting leishmaniasis.
Topoisomerase I inhibitor 9 is a selective inhibitor of leishmanial topoisomerase IB, demonstrating significant antileishmanial activity against Leishmania donovani promastigotes. The compound exhibits an IC50 value of 34.81 μM, indicating its potential utility in research aimed at developing therapeutic strategies for leishmaniasis. This reagent is valuable for studies focusing on the role of topoisomerases in parasite biology and drug discovery efforts targeting leishmaniasis.
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