Topoisomerase II inhibitor 15

Catalog No.: A31944
Topoisomerase II Inhibitor
Topoisomerase II Inhibitor 15 is a selective inhibitor of topoisomerase II, an enzyme critical for DNA replication and repair. This compound induces apoptosis and exhibits potent activity against head and neck tumors, making it a valuable tool for cancer research. Its mechanism of action further highlights its potential in studying the roles of topoisomerases in tumor biology and therapeutics.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTopoisomerase II Inhibitor 15 is a selective inhibitor of topoisomerase II, an enzyme critical for DNA replication and repair. This compound induces apoptosis and exhibits potent activity against head and neck tumors, making it a valuable tool for cancer research. Its mechanism of action further highlights its potential in studying the roles of topoisomerases in tumor biology and therapeutics.
Product Information
Catalog NumA31944
FormulaC15H11Cl2N5
Molecular Weight332.19
CAS Number451516-79-3
SMILESClC1=CC=C(C2N=C(N)N=C3NC4=C(N32)C=CC=C4)C=C1Cl
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