Topoisomerase II Inhibitor 18 is a quinoxaline derivative that selectively inhibits topoisomerase II with an IC50 of 7.5 μM. This compound effectively suppresses cell proliferation and induces G1/S phase cell cycle arrest, leading to apoptosis in PC-3 cancer cells. It demonstrates significant antitumor activity, making it a valuable tool for cancer research applications focused on topoisomerase II modulation.
Topoisomerase II Inhibitor 18 is a quinoxaline derivative that selectively inhibits topoisomerase II with an IC50 of 7.5 μM. This compound effectively suppresses cell proliferation and induces G1/S phase cell cycle arrest, leading to apoptosis in PC-3 cancer cells. It demonstrates significant antitumor activity, making it a valuable tool for cancer research applications focused on topoisomerase II modulation.
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