Topoisomerase II inhibitor 8

Catalog No.: A57210
Topoisomerase II Inhibitor
Topoisomerase II Inhibitor 8 is a potent inhibitor of topoisomerase II, demonstrating an IC50 of 0.52 μM. This compound exhibits significant anti-proliferative activity, effectively arresting the cell cycle at the G2/M phase. It is suitable for research applications involving cancer cell growth and the study of cell cycle regulation.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTopoisomerase II Inhibitor 8 is a potent inhibitor of topoisomerase II, demonstrating an IC50 of 0.52 μM. This compound exhibits significant anti-proliferative activity, effectively arresting the cell cycle at the G2/M phase. It is suitable for research applications involving cancer cell growth and the study of cell cycle regulation.
Product Information
Catalog NumA57210
FormulaC14H8N4O3S
Molecular Weight312.30
CAS Number2493298-68-1
SMILESO=C(C1=CC=CO1)SC2=NN=C3N2C4=C(C=CC=C4)NC3=O
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