Topoisomerase IIα-IN-8 is an inhibitor of human DNA topoisomerase IIα (htIIα), characterized by an IC50 value of 462 ± 38.0 μM. This compound is utilized in research focused on unraveling the mechanisms of DNA topology modification and the role of topoisomerases in cellular processes. Its applications extend to studies in cancer biology, particularly in evaluating the effects of topoisomerase inhibition on cell proliferation and apoptosis.
Topoisomerase IIα-IN-8 is an inhibitor of human DNA topoisomerase IIα (htIIα), characterized by an IC50 value of 462 ± 38.0 μM. This compound is utilized in research focused on unraveling the mechanisms of DNA topology modification and the role of topoisomerases in cellular processes. Its applications extend to studies in cancer biology, particularly in evaluating the effects of topoisomerase inhibition on cell proliferation and apoptosis.
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