Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that serves as a moderate inhibitor of DNA topoisomerase II, with an IC50 value of 571 μM. This compound demonstrates notable cell growth inhibition, exhibiting IC50 values of 117 μM in K562 cells and 218 μM in CHO cells. Topoisomerase IIα-IN-9 is valuable for research applications focused on cancer biology and the mechanisms of drug resistance.
Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that serves as a moderate inhibitor of DNA topoisomerase II, with an IC50 value of 571 μM. This compound demonstrates notable cell growth inhibition, exhibiting IC50 values of 117 μM in K562 cells and 218 μM in CHO cells. Topoisomerase IIα-IN-9 is valuable for research applications focused on cancer biology and the mechanisms of drug resistance.
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