Biological Activity
Toreforant is a potent and selective histamine H4 receptor (H4R) antagonist, with a Ki at the human receptor of 8.4 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.48 mL | 127.38 mL | 254.75 mL |
0.5 mM | 5.1 mL | 25.48 mL | 50.95 mL |
1 mM | 2.55 mL | 12.74 mL | 25.48 mL |
5 mM | 0.51 mL | 2.55 mL | 5.1 mL |
*The above data is based on the productmolecular weight 392.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21058 |
---|---|
Actions | Antagonist |
M. Wt | 392.54 |
Formula | C23H32N6 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 952494-46-1 |
Synonyms | JNJ-38518168, JNJ38518168, JNJ 38518168 |
SMILES | CN1CCC(CCCNC2=NC=C(C3=NC4=CC(C)=CC(C)=C4N3)C(C)=N2)CC1 |
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