TP0591816

Catalog No.: A53189
RSV Inhibitor
TP0591816 is a highly potent dual inhibitor targeting both wild-type and mutant respiratory syncytial virus (RSV) fusion proteins, exhibiting effective inhibition with EC50 values of 0.27 nM for wild-type and 0.70 nM for the D486N mutant. This compound demonstrates significant antiviral activity, making it a valuable tool for RSV research and potential therapeutic development. Researchers can utilize TP0591816 to explore mechanisms of RSV pathogenesis and evaluate antiviral strategies against this respiratory virus.
Grouped product items
Size Price Stock Qty
5mg
$795.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTP0591816 is a highly potent dual inhibitor targeting both wild-type and mutant respiratory syncytial virus (RSV) fusion proteins, exhibiting effective inhibition with EC50 values of 0.27 nM for wild-type and 0.70 nM for the D486N mutant. This compound demonstrates significant antiviral activity, making it a valuable tool for RSV research and potential therapeutic development. Researchers can utilize TP0591816 to explore mechanisms of RSV pathogenesis and evaluate antiviral strategies against this respiratory virus.
Product Information
Catalog NumA53189
FormulaC27H31ClN6O4
Molecular Weight539.03
CAS Number2448519-26-2
SMILESCN1C2=CC([C@]3([H])C[C@H](C3)O)=NC4=CC([C@@]5([H])N(CCCC5)C(C6=CC(Cl)=CC=C6OCC(NCC1)=O)=O)=NN24
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