TPKI-39 is an inhibitor of DDR1, DDR2, and FLT1, demonstrating a human DDR1 IC50 of 380 nM and human DDR2 IC50 of 120 nM. It effectively inhibits enzymatic activity and autophosphorylation of DDR1 and DDR2, as well as FLT1 enzymatic activity, with an IC50 of 65 nM. This compound is useful for studies focused on the modulation of receptor tyrosine kinases and collagen-mediated signaling pathways.
TPKI-39 is an inhibitor of DDR1, DDR2, and FLT1, demonstrating a human DDR1 IC50 of 380 nM and human DDR2 IC50 of 120 nM. It effectively inhibits enzymatic activity and autophosphorylation of DDR1 and DDR2, as well as FLT1 enzymatic activity, with an IC50 of 65 nM. This compound is useful for studies focused on the modulation of receptor tyrosine kinases and collagen-mediated signaling pathways.
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