Catalog No.: A17118

Integrin Antagonist


TR-14035 Chemical Structure

CAS NO. 232271-19-1

TR-14035 is a dual antagonist of α4β7 and α4β1 integrins.

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Biological Activity

TR-14035 is a dual antagonist of α4β7 and α4β1 integrins.
In vitro DMSO 84 mg/mL (177.09 mM)
Water Insoluble
Ethanol 18 mg/mL (37.94 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.08 mL 105.41 mL 210.82 mL
0.5 mM 4.22 mL 21.08 mL 42.16 mL
1 mM 2.11 mL 10.54 mL 21.08 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 474.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17118
Actions Antagonist
CAS No. 232271-19-1
Formula C24H21Cl2NO5
M. Wt 474.33
Purity >98%
Synonyms TR 14035, TR14035
SMILES O=C(O)[[email protected]](CC1=CC=C(C2=C(OC)C=CC=C2OC)C=C1)NC(C3=C(Cl)C=CC=C3Cl)=O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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