TRAM-34

Catalog No.: A12783

Potassium Channel Blocker

TRAM-34

TRAM-34 Chemical Structure

CAS NO. 289905-88-0

TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $45.00

Special Price $36.00

25 mg

Regular Price: $90.00

Special Price $72.00

50 mg

Regular Price: $135.00

Special Price $108.00

100 mg

Regular Price: $225.00

Special Price $180.00

Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.
Targets
IKCa1 (KCa3.1)
20 nM(Kd)
In vitro (25°C) DMSO 0.36 mg/mL (1.04 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+corn oil 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29 mL 144.99 mL 289.99 mL
0.5 mM 5.8 mL 29 mL 58 mL
1 mM 2.9 mL 14.5 mL 29 mL
5 mM 0.58 mL 2.9 mL 5.8 mL

*The above data is based on the productmolecular weight 344.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12783
Actions Blocker
CAS No. 289905-88-0
Formula C22H17ClN2
M. Wt 344.84
Purity >98%
Synonyms TRAM34, TRAM 34
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3Cl)N4C=CC=N4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy TRAM-34 | TRAM-34 Supplier | purchase | cost | manufacturer | order | distributor | buy 289905-88-0| 289905-88-0 Supplier | purchase 289905-88-0 | 289905-88-0 cost | 289905-88-0 manufacturer | order 289905-88-0 | 289905-88-0 distributor
Rewards