Tramadol N-oxide is a derivative of tramadol that primarily targets analgesic pathways. It produces dose-dependent, long-lasting antinociception through its affinity for the μ-opioid receptor (Ki = 38.5 μM) while exhibiting weaker interactions with δ and κ receptors (Ki > 100 μM). This compound is valuable for research into analgesic effects and the mechanisms underlying pain relief.
Tramadol N-oxide is a derivative of tramadol that primarily targets analgesic pathways. It produces dose-dependent, long-lasting antinociception through its affinity for the μ-opioid receptor (Ki = 38.5 μM) while exhibiting weaker interactions with δ and κ receptors (Ki > 100 μM). This compound is valuable for research into analgesic effects and the mechanisms underlying pain relief.
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