trans-Thalidomide-1,4-cyclohexanediamine is an E3 ligase-linker conjugate utilized in the synthesis of PROTACs. This compound serves as a crucial building block for developing PROTACs, such as CL-F-B1, which demonstrates potent activity in degrading PD-L1 and has significant anticancer effects. Its application in PROTAC technology facilitates targeted degradation of specific proteins, making it valuable in cancer research and therapeutic development.
trans-Thalidomide-1,4-cyclohexanediamine is an E3 ligase-linker conjugate utilized in the synthesis of PROTACs. This compound serves as a crucial building block for developing PROTACs, such as CL-F-B1, which demonstrates potent activity in degrading PD-L1 and has significant anticancer effects. Its application in PROTAC technology facilitates targeted degradation of specific proteins, making it valuable in cancer research and therapeutic development.
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