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- Bhat L,et al. Evaluation of the effects of RP5063, a novel, multimodal, serotonin receptor modulator, as single-agent therapy and co-administrated with sildenafil, bosentan, and treprostinil in a monocrotaline-induced pulmonary arterial hypertension rat model, Eur J Pharmacol, 2018, May 15;827:159-166 29453947
|Storage||at -20°C 3 years Powder|
|SMILES code||CCCCC[[email protected]@H](CC[[email protected]]1[[email protected]@H](C[[email protected]]2[[email protected]@H]1CC3=C(C2)C(=CC=C3)OCC(=O)O)O)O|
|Treprostinil is a stable analog of prostacyclin that is used clinically for the treatment of PPH.|
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||25.61 mL||128.04 mL||256.08mL|
|0.5 mM||5.12 mL||25.61 mL||51.22 mL|
|1 mM||2.56 mL||12.8 mL||25.61 mL|
|5 mM||0.51 mL||2.56 mL||5.12 mL|
*The above data is based on the productmolecular weight 390.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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