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Tri-SM6.1

Catalog No.: B21824
Integrin αvβ6 Ligand
Tri-SM6.1 is a tridentate small-molecule ligand that specifically targets integrin αvβ6. This compound effectively binds to integrin αvβ6 on epithelial cells, facilitating the delivery of conjugated α-ENaC RNA interference agents. Its biological activity and targeting capability make it a valuable tool for research applications focused on epithelial cell signaling and RNAi-mediated gene regulation.
Tri-SM6.1 2851077-05-7 Integrin αvβ6 Ligand
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTri-SM6.1 is a tridentate small-molecule ligand that specifically targets integrin αvβ6. This compound effectively binds to integrin αvβ6 on epithelial cells, facilitating the delivery of conjugated α-ENaC RNA interference agents. Its biological activity and targeting capability make it a valuable tool for research applications focused on epithelial cell signaling and RNAi-mediated gene regulation.
Product Information
Catalog NumB21824
FormulaC159H209N25O39
Molecular Weight3094.50
CAS Number2851077-05-7
SMILESO=C(NCCOCCOCC1=CN(CCOCCOCCOCCOCCOC2=CC=C(C3=CC=C(C=C3)[C@H](CC(O)=O)NC(CNC(CCCNC4=CC(C)=CC=N4)=O)=O)C5=C2C=CC=C5)N=N1)CCC(CCC(NCCOCCOCC6=CN(CCOCCOCCOCCOCCOC7=CC=C(C8=CC=C(C=C8)[C@H](CC(O)=O)NC(CNC(CCCNC9=CC(C)=CC=N9)=O)=O)C%10=C7C=CC=C%10)N=N6)=O)(CCC(NCCOCCOCC(N=N%11)=CN%11CCOCCOCCOCCOCCOC%12=CC=C(C%13=C%12C=CC=C%13)C%14=CC=C([C@@H](NC(CNC(CCCNC%15=CC(C)=CC=N%15)=O)=O)CC(O)=O)C=C%14)=O)NC(CCCC(O)=O)=O
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Cytoskeleton > Integrin