Triisopropyl phosphate is an estradiol inhibitor that exerts anti-estrogenic activity by inhibiting TFF1 and EGR3 gene expression. It demonstrates the ability to suppress estradiol-induced proliferation in MCF-7 cells, with an EC50 of 341 μM. Additionally, it inhibits estrogen response element (ERE)-stimulated luciferase activity in MVLN cells with an EC50 of 900 μM, making it a valuable tool for research in estrogen signaling pathways.
Triisopropyl phosphate is an estradiol inhibitor that exerts anti-estrogenic activity by inhibiting TFF1 and EGR3 gene expression. It demonstrates the ability to suppress estradiol-induced proliferation in MCF-7 cells, with an EC50 of 341 μM. Additionally, it inhibits estrogen response element (ERE)-stimulated luciferase activity in MVLN cells with an EC50 of 900 μM, making it a valuable tool for research in estrogen signaling pathways.
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