Trimipramine-d3 maleate is a deuterium-labeled analog of Trimipramine maleate, functioning primarily as a selective antagonist of 5-HT receptors. It exhibits pKis of 6.39 for 5-HT1C, 8.10 for 5-HT2, and 4.66 for 5-HT1A, highlighting its specificity towards serotonin signaling pathways. This stable isotope is valuable for pharmacokinetic studies and metabolic tracing in biological research, providing insights into the pharmacodynamics of serotonergic modulation.
Trimipramine-d3 maleate is a deuterium-labeled analog of Trimipramine maleate, functioning primarily as a selective antagonist of 5-HT receptors. It exhibits pKis of 6.39 for 5-HT1C, 8.10 for 5-HT2, and 4.66 for 5-HT1A, highlighting its specificity towards serotonin signaling pathways. This stable isotope is valuable for pharmacokinetic studies and metabolic tracing in biological research, providing insights into the pharmacodynamics of serotonergic modulation.
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