TTP-22

Catalog No.: A14101

CK2 inhibitor

TTP-22

TTP-22 Chemical Structure

CAS NO. 329907-28-0

TTP 22 is a high affinity, casein kinase 2 (CK2) inhibitor (IC50= 0.1uM, Ki= 40nM). In addition, TTP 22 shows selectivity for CK2 over JNK3, ROCK1, and MET (inhibitory effects displayed at greater than 10 uM). TTP 22 is highly conserved serine/threonine protein kinase that is also involved in cell proliferation, cell differentiation and apoptosis.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$200.00
50 mg
$300.00
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Biological Activity

TTP 22 is a high affinity, casein kinase 2 (CK2) inhibitor (IC50= 0.1uM, Ki= 40nM). In addition, TTP 22 shows selectivity for CK2 over JNK3, ROCK1, and MET (inhibitory effects displayed at greater than 10 uM). TTP 22 is highly conserved serine/threonine protein kinase that is also involved in cell proliferation, cell differentiation and apoptosis.
In vitro DMSO 63 mg/mL (190.66 mM)
Water Insoluble
Ethanol 8 mg/mL (24.21 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 30.26 mL 151.32 mL 302.65 mL
0.5 mM 6.05 mL 30.26 mL 60.53 mL
1 mM 3.03 mL 15.13 mL 30.26 mL
5 mM 0.61 mL 3.03 mL 6.05 mL

*The above data is based on the productmolecular weight 330.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14101
Actions Inhibitor
CAS No. 329907-28-0
Formula C16H14N2O2S2
M. Wt 330.42
Solubility DMSO
Purity >98%
Synonyms TTP 22, TTP22
SMILES CC1=CC=C(C=C1)C2=CSC3=C2C(=NC=N3)SCCC(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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