TWIK-1/TREK-1-IN-2 is a specific inhibitor of the TWIK-1 and TREK-1 potassium channels. It demonstrates inhibitory activity against TREK-1 homodimers and TWIK-1/TREK-1 heterodimers with IC50 values of 10.13 μM and 15.5 μM, respectively. This compound has potential applications in antidepressant research, particularly in studies focusing on the modulation of mood and anxiety disorders.
TWIK-1/TREK-1-IN-2 is a specific inhibitor of the TWIK-1 and TREK-1 potassium channels. It demonstrates inhibitory activity against TREK-1 homodimers and TWIK-1/TREK-1 heterodimers with IC50 values of 10.13 μM and 15.5 μM, respectively. This compound has potential applications in antidepressant research, particularly in studies focusing on the modulation of mood and anxiety disorders.
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