TX1-85-1

Catalog No.: A16361

Her3 (ErbB3) ligand

TX1-85-1

TX1-85-1 Chemical Structure

CAS NO. 1603845-32-4

TX1-85-1 is ErbB3 inhibitor. TX2-121-1 may exert Her3-dependent pharmacology through an allosteric mechanismthereby disrupting interactions between Her3 and other proteins such as Her3 or cMet consistent with results presented here and distinct from conventional kinase inhibitors, which block catalytic function.

Availability: In stock

Package Price Qty
5 mg
$160.00
10 mg
$300.00
50 mg
$900.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

TX1-85-1 is ErbB3 inhibitor. TX2-121-1 may exert Her3-dependent pharmacology through an allosteric mechanismthereby disrupting interactions between Her3 and other proteins such as Her3 or cMet consistent with results presented here and distinct from conventional kinase inhibitors, which block catalytic function.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.22 mL 86.1 mL 172.21 mL
0.5 mM 3.44 mL 17.22 mL 34.44 mL
1 mM 1.72 mL 8.61 mL 17.22 mL
5 mM 0.34 mL 1.72 mL 3.44 mL

*The above data is based on the productmolecular weight 580.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A16361
Actions Inhibitor
M. Wt 580.69
Formula C32H36N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1603845-32-4
Synonyms TX1 85-1, TX185-1, TX1851, TX 1851, TX-1851
SMILES C=CC(NC1=CC(C2=NN(C3CCC(N4CCN(C(C)=O)CC4)CC3)C5=NC=NC(N)=C52)=CC=C1OC6=CC=CC=C6)=O

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