(±)-U-50488 ((±)-trans-(1R,2R)-U-50488)

Catalog No.: A62593
Kappa Opioid Receptor Agonist
(±)-U-50488 is a selective agonist of the kappa opioid receptor. It has been shown to improve symptoms associated with status epilepticus, while exhibiting minimal impact on spontaneous seizure occurrences. This compound is valuable for research focused on epilepsy and its underlying mechanisms.
Grouped product items
Size Price Stock Qty
5mg
$350.00
In stock
10mg
$650.00
In stock
50mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(±)-U-50488 is a selective agonist of the kappa opioid receptor. It has been shown to improve symptoms associated with status epilepticus, while exhibiting minimal impact on spontaneous seizure occurrences. This compound is valuable for research focused on epilepsy and its underlying mechanisms.
Product Information
Catalog NumA62593
FormulaC19H26Cl2N2O
Molecular Weight369.33
CAS Number67198-13-4
SMILESClC(C=C1CC(N([C@H]2[C@H](N3CCCC3)CCCC2)C)=O)=C(C=C1)Cl
Synonyms(±)-trans-(1R,2R)-U-50488
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