U-89843A hydrochloride

Catalog No.: A66850
GABAA Receptors PAM
U-89843A hydrochloride is a positive allosteric modulator (PAM) of GABAA receptors. It enhances GABA-induced chloride currents across the α1β2γ2, α3β2γ2, and α6β2γ2 subtypes, contributing to its biological activity. This compound also exhibits antioxidant and sedative effects, making it a valuable tool for research into neurological disorders and the modulation of inhibitory neurotransmission.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionU-89843A hydrochloride is a positive allosteric modulator (PAM) of GABAA receptors. It enhances GABA-induced chloride currents across the α1β2γ2, α3β2γ2, and α6β2γ2 subtypes, contributing to its biological activity. This compound also exhibits antioxidant and sedative effects, making it a valuable tool for research into neurological disorders and the modulation of inhibitory neurotransmission.
Product Information
Catalog NumA66850
FormulaC16H24ClN5
Molecular Weight321.85
CAS Number157013-85-9
SMILESCN1C(C)=CC2=C(N3CCCC3)N=C(N4CCCC4)N=C21.[H]Cl
SynonymsPNU-89843 hydrochloride
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