UFP-101 is a selective and competitive antagonist of the NOP receptor, exhibiting a pKi of 10.24. It demonstrates greater than 3000-fold selectivity over delta, mu, and kappa opioid receptors. UFP-101 has been shown to produce antidepressant-like effects, making it a valuable tool for research into mood disorders and the role of NOP receptor signaling.
UFP-101 is a selective and competitive antagonist of the NOP receptor, exhibiting a pKi of 10.24. It demonstrates greater than 3000-fold selectivity over delta, mu, and kappa opioid receptors. UFP-101 has been shown to produce antidepressant-like effects, making it a valuable tool for research into mood disorders and the role of NOP receptor signaling.
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