UK-371800 is a highly selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 of 4.2 nM. This compound demonstrates favorable permeability characteristics and remains unaffected by P-glycoprotein efflux mechanisms. UK-371800 is primarily utilized in research applications related to erectile dysfunction and pulmonary hypertension, contributing to the understanding of cGMP signaling pathways in cardiovascular health.
UK-371800 is a highly selective phosphodiesterase 5 (PDE5) inhibitor, exhibiting an IC50 of 4.2 nM. This compound demonstrates favorable permeability characteristics and remains unaffected by P-glycoprotein efflux mechanisms. UK-371800 is primarily utilized in research applications related to erectile dysfunction and pulmonary hypertension, contributing to the understanding of cGMP signaling pathways in cardiovascular health.
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