UK 5099

Catalog No.: A13038
MCT Inhibitor
UK 5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC); inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
Grouped product items
Product Name Price Stock Qty
UK 5099 10mg
$90.00
In stock
UK 5099 25mg
$180.00
In stock
UK 5099 50mg
$300.00
In stock
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Adooq Products cited in reputable paper
Biological Activity
Discription UK 5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC); inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
Product Information
Catalog Num A13038
Formula C18H12N2O2
Molecular Weight 288.3
CAS Number 56396-35-1
SMILES C1=CC=C(C=C1)N2C=C(C3=CC=CC=C32)C=C(C#N)C(=O)O
Synonyms PF-1005023, UK5099, UK-5099, PF1005023, PF 1005023
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 54 mg/mL (187.3 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.69 mL 173.43 mL 346.86 mL
0.5 mM 6.94 mL 34.69 mL 69.37 mL
1 mM 3.47 mL 17.34 mL 34.69 mL
5 mM 0.69 mL 3.47 mL 6.94 mL
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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