UK 5099

Catalog No.: A13038

MCT Inhibitor

UK 5099

UK 5099 Chemical Structure

CAS NO. 56396-35-1

UK 5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC); inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$300.00
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Biological Activity

UK 5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC); inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
In vitro DMSO 54 mg/mL (187.3 mM)
Water Insoluble
Ethanol <1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.69 mL 173.43 mL 346.86 mL
0.5 mM 6.94 mL 34.69 mL 69.37 mL
1 mM 3.47 mL 17.34 mL 34.69 mL
5 mM 0.69 mL 3.47 mL 6.94 mL

*The above data is based on the productmolecular weight 288.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13038
Actions Inhibitor
CAS No. 56396-35-1
Formula C18H12N2O2
M. Wt 288.3
Purity >98%
Synonyms PF-1005023, UK5099, UK-5099, PF1005023, PF 1005023
SMILES C1=CC=C(C=C1)N2C=C(C3=CC=CC=C32)C=C(C#N)C(=O)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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