Catalog No.: A13166

EZH2/EZH1 Inhibitor


UNC-1999 Chemical Structure

CAS NO. 1431612-23-5

UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.

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5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

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Special Price $88.00

25 mg

Regular Price: $220.00

Special Price $176.00

50 mg

Regular Price: $350.00

Special Price $280.00

10mM * 1mL in DMSO

Regular Price: $127.00

Special Price $101.60

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48

Biological Activity

UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.
EZH2 (Cell-free assay) EZH1 (Cell-free assay)
2 nM45 nM
In vitro DMSO 17 mg/mL (29.84 mM)
Water Insoluble
Ethanol 43 mg/mL (75.47 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.55 mL 87.76 mL 175.52 mL
0.5 mM 3.51 mL 17.55 mL 35.1 mL
1 mM 1.76 mL 8.78 mL 17.55 mL
5 mM 0.35 mL 1.76 mL 3.51 mL

*The above data is based on the productmolecular weight 569.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13166
Actions Inhibitor
CAS No. 1431612-23-5
Formula C33H43N7O2
M. Wt 569.74
Purity >98%
Synonyms UNC 1999, UNC1999

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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