Catalog No.: A13166
EZH2/EZH1 Inhibitor
UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.
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Product Name Price Stock Qty
UNC-1999 5mg
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UNC-1999 10mg
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UNC-1999 25mg
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UNC-1999 50mg
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UNC-1999 10mM * 1mL in DMSO
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's UNC-1999 has been cited by 1 publications
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • Biological Activity
    Discription UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.
    Target Value
    Product Information
    Catalog Num A13166
    Formula C33H43N7O2
    Molecular Weight 569.74
    CAS Number 1431612-23-5
    Synonyms UNC 1999, UNC1999

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro DMSO 17 mg/mL (29.84 mM)
    Water Insoluble
    Ethanol 43 mg/mL (75.47 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.55 mL 87.76 mL 175.52 mL
    0.5 mM 3.51 mL 17.55 mL 35.1 mL
    1 mM 1.76 mL 8.78 mL 17.55 mL
    5 mM 0.35 mL 1.76 mL 3.51 mL
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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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