Total item
Cart Subtotal
$0.00 - Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
Biological Activity
UNC1999 is the first orally bioavailable inhibitor that has high in vitro potency for wildtype and mutant EZH2 as well as EZH1.
Targets
| EZH2 (Cell-free assay) | EZH1 (Cell-free assay) | |||
| 2 nM | 45 nM |
| In vitro | DMSO | 17 mg/mL (29.84 mM) | |
| Water | Insoluble | ||
| Ethanol | 43 mg/mL (75.47 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.55 mL | 87.76 mL | 175.52 mL |
| 0.5 mM | 3.51 mL | 17.55 mL | 35.1 mL |
| 1 mM | 1.76 mL | 8.78 mL | 17.55 mL |
| 5 mM | 0.35 mL | 1.76 mL | 3.51 mL |
*The above data is based on the productmolecular weight 569.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13166 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1431612-23-5 |
| Formula | C33H43N7O2 |
| M. Wt | 569.74 |
| Purity | >98% |
| Synonyms | UNC 1999, UNC1999 |
| SMILES | CCCC1=C(C(=O)NC(=C1)C)CNC(=O)C2=C3C=NN(C3=CC(=C2)C4=CN=C(C=C4)N5CCN(CC5)C(C)C)C(C)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy UNC-1999 | UNC-1999 Supplier | purchase | cost | manufacturer | order | distributor | buy 1431612-23-5| 1431612-23-5 Supplier | purchase 1431612-23-5 | 1431612-23-5 cost | 1431612-23-5 manufacturer | order 1431612-23-5 | 1431612-23-5 distributor
Adooq Quality Guarantee
We promise all products perform as described.