UR 1102

Catalog No.: A16187

URAT1 inhibitor

UR 1102

UR 1102 Chemical Structure

CAS NO. 1198153-15-9

UR 1102, inhibitor of the renal urate transporter URAT1 with high selectivity to URAT1 over OAT1 and OAT3 in vitro (Ki values 0.057 uM, 7.2 uM, and 2.4 uM, respectively), capable of increasing the fractional excretion of urinary uric acid, and reducing plasma uric acid more effectively than Benzbromarone.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$160.00
50 mg
$620.00
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Biological Activity

UR 1102, inhibitor of the renal urate transporter URAT1 with high selectivity to URAT1 over OAT1 and OAT3 in vitro (Ki values 0.057 uM, 7.2 uM, and 2.4 uM, respectively), capable of increasing the fractional excretion of urinary uric acid, and reducing plasma uric acid more effectively than Benzbromarone.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.15 mL 120.76 mL 241.52 mL
0.5 mM 4.83 mL 24.15 mL 48.3 mL
1 mM 2.42 mL 12.08 mL 24.15 mL
5 mM 0.48 mL 2.42 mL 4.83 mL

*The above data is based on the productmolecular weight 414.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16187
Actions Inhibitor
CAS No. 1198153-15-9
Formula C14H10Br2N2O3
M. Wt 414.05
Purity >98%
Synonyms UR-1102
SMILES C1COC2=C(N1C(=O)C3=CC(=C(C(=C3)Br)O)Br)C=NC=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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