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UR-12633

Catalog No.: A62952
PAF Antagonist
UR-12633 is a potent platelet-activating factor (PAF) antagonist. It effectively reverses hypotension, inhibits coagulation abnormalities, and decreases vascular permeability and metabolic disorders in rodent models of endotoxic shock. This compound is valuable for studying the mechanisms and treatment strategies for endotoxic shock.
UR-12633 179912-83-5 PAF Antagonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionUR-12633 is a potent platelet-activating factor (PAF) antagonist. It effectively reverses hypotension, inhibits coagulation abnormalities, and decreases vascular permeability and metabolic disorders in rodent models of endotoxic shock. This compound is valuable for studying the mechanisms and treatment strategies for endotoxic shock.
Product Information
Catalog NumA62952
FormulaC27H27N3O
Molecular Weight409.53
CAS Number179912-83-5
SMILESN#CC(C=1C=NC=CC1)C2CCN(C(=O)CC(C=3C=CC=CC3)C=4C=CC=CC4)CC2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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GPCR/G Protein > Platelet-Activating Factor (PAF) Receptors