UR-AK49 is a potent agonist of the human histamine H1 and H2 receptors. It exhibits an EC50 value of 23 nM in a GTPase assay utilizing the hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. This compound is relevant for applications in neurobiology and offers potential insights into histamine receptor functions in various physiological processes.
UR-AK49 is a potent agonist of the human histamine H1 and H2 receptors. It exhibits an EC50 value of 23 nM in a GTPase assay utilizing the hH2R-Gsalpha fusion protein expressed in Sf9 insect cells. This compound is relevant for applications in neurobiology and offers potential insights into histamine receptor functions in various physiological processes.
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