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$0.00 - Md Shah Sufian, .et al. Early suppression of the endocannabinoid degrading enzymes FAAH and MAGL alters locomotor development in zebrafish, J Exp Biol, 2021, 21 JUNE
- Toshihiko Tsutsumi, .et al. Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells, Biochim Biophys Acta Mol Cell Biol Lipids, 2020, Sep;1865(9):158761 PMID: 32629025
Biological Activity
URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).
Targets
| FAAH | ||||
| 4.6 nM |
| In vitro (25°C) | DMSO | 62 mg/mL (183.21 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (14.77 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.55 mL | 147.75 mL | 295.51 mL |
| 0.5 mM | 5.91 mL | 29.55 mL | 59.1 mL |
| 1 mM | 2.96 mL | 14.78 mL | 29.55 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.91 mL |
*The above data is based on the productmolecular weight 338.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11049 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 546141-08-6 |
| Formula | C20H22N2O3 |
| M. Wt | 338.4 |
| Purity | >98% |
| Synonyms | KDS-4103, URB-597 |
| SMILES | C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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