Val-Ala-PAB

Catalog No.: A42622
ADC Linker
Val-Ala-PAB is a cleavable ADC linker that facilitates the synthesis of antibody-drug conjugates (ADCs). This linker is designed to enhance the stability and efficacy of ADCs by enabling controlled release of the cytotoxic payload upon internalization. It is particularly useful in cancer research applications where targeted delivery of therapeutics is paramount.
Grouped product items
Size Price Stock Qty
10mg
$25.00
In stock
100mg
$40.00
In stock
250mg
$70.00
In stock
1g
$245.00
In stock
5g
$620.00
In stock
10g
$925.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVal-Ala-PAB is a cleavable ADC linker that facilitates the synthesis of antibody-drug conjugates (ADCs). This linker is designed to enhance the stability and efficacy of ADCs by enabling controlled release of the cytotoxic payload upon internalization. It is particularly useful in cancer research applications where targeted delivery of therapeutics is paramount.
Product Information
Catalog NumA42622
FormulaC15H23N3O3
Molecular Weight293.37
CAS Number1343476-44-7
SMILESCC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O
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